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How Has the Advanced Therapy Medicinal Products Contract Development And Manufacturing Organization (CDMO) Market Size Evolved Over the Last Few Years?
In the past few years, the market size of the contract development and manufacturing organization (CDMO) for advanced therapy medicinal products (ATMPs) has witnessed a significant expansion. The valuation is projected to escalate from $5.31 billion in 2024 to around $6.2 billion in 2025, marking an impressive compound annual growth rate (CAGR) of 16.7%. The unprecedented growth during the historical period stems from a variety of factors, including an upswing in the number of ATMP clinical trials, increasing faith and awareness among research entities about the potential benefits of progressive therapies, the existence of numerous ATMP CDMOs, amplified endeavors to formulate new treatments for multifarious diseases, and encouraging policies implemented by the government.
The market size for advanced therapy medicinal products contract development and manufacturing organization (CDMO) is predicted to experience a substantial increase in the next few years. It is anticipated to reach a value of $11.12 billion by 2029 with a compound annual growth rate (CAGR) of 15.7%. This growth during the forecast period can be attributed to several key factors. These include the substantial investment by CDMOs, the rise in the number of new entrants in the cell and gene therapy (CGT) industry, an increase in funding and investment for cell and gene development, a rise in pharmaceutical research and development expenditure, and an increased number of clinical trials for ATMPs. Other significant developments expected during the forecast period include upgrades in AAV biomanufacturing facilities, expansion in the cell and gene therapy manufacturing, technological improvements in the cell and gene therapy field, a growing necessity for access to advanced platforms and technologies, and the adoption of pioneering technologies such as CRISPR and next-generation sequencing for improved accuracy.
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What’s Driving the Upward Growth Trajectory of the Advanced Therapy Medicinal Products Contract Development And Manufacturing Organization (CDMO) Market?
The advanced therapy medicinal products CDMO market’s growth is likely to be spurred by the rising number of clinical trials. Clinical trials are research studies involving humans that assess the safety and effectiveness of various medical interventions, including drugs, treatments, and preventative measures.
There is a surge in the number of clinical trials to cater to the growing demand for ground-breaking treatments and to tackle the escalating global disease crisis. The adoption of advanced therapy medicinal products escalates the need for CDMO manufacturing services, capitalizing on their specialized skills and infrastructure. The data gathered from clinical trials contributes to refining manufacturing, ensures scalability, and upholds quality to cater to broader clinical and commercial requirements. As per the Association of the British Pharmaceutical Industry, a trade association based in the UK, there was a slight increase of 4.3% in the total number of industry clinical trials launched in the UK annually, from 394 in 2021 to 411 in 2022. Hence, the expansion of the advanced therapy medicinal products CDMO market can be attributed to the surge in clinical trials.
Which Segments in the Advanced Therapy Medicinal Products Contract Development And Manufacturing Organization (CDMO) Industry Are Seeing the Fastest Growth?
The advanced therapy medicinal products contract development and manufacturing organization (cdmo)market covered in this report is segmented –
1) By Product: Gene Therapy; Cell Therapy; Tissue Engineered
2) By Phase: Phase I; Phase II; Phase III; Phase IV
3) By Indication: Oncology; Cardiology; Central Nervous System And Musculoskeletal; Infectious Disease; Dermatology; Endocrine, Metabolic, Genetic; Immunology And Inflammation; Ophthalmology; Hematology
Subsegments:
1) By Gene Therapy: Viral Vectors; Non-Viral Vectors; Dna Or Rna-Based Products
2) By Cell Therapy: Autologous Cell Therapy; Allogeneic Cell Therapy; Stem Cell Therapy
3) By Tissue Engineered: Skin Substitutes; Cartilage And Bone Tissue; Vascular Grafts And Organs
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How Will Shifting Market Trends Influence Advanced Therapy Medicinal Products Contract Development And Manufacturing Organization (CDMO) System Adoption?
Prominent players in the advanced therapy medicinal products CDMO market are innovating cell therapy manufacturing services in an effort to resolve critical challenges in cell therapy production and accelerate the development processes of their partners. These services offered by contract development and manufacturing organizations encompass everything from early preclinical development to late-stage clinical trials and commercialization. For Instance, in January 2024, Pluristem Therapeutics Inc., a biotech company based in Israel that specializes in converting cells into solutions, initiated a new business sector called PluriCDMO which focuses on cell therapy manufacturing. PluriCDMO leverages a patented bioreactor system enabling 3D cell multiplication, which assists in generating various types of cells including stem cells, induced pluripotent stem cells, exosomes, and immune therapies. PluriCDMO aims to deliver high-quality, crucial medicines to patients whilst ensuring exceptional consistency between batches in a scalable, budget-friendly framework under good manufacturing practice conditions.
Which Global Regions Are Powering Demand in the Advanced Therapy Medicinal Products Contract Development And Manufacturing Organization (CDMO) Market?
North America was the largest region in the advanced therapy medicinal product contract development and manufacturing organization (CDMO) market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the advanced therapy medicinal products contract development and manufacturing organization (CDMO) market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.
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How Key Players Are Driving Growth in the Advanced Therapy Medicinal Products Contract Development And Manufacturing Organization (CDMO) Market?
Major companies operating in the advanced therapy medicinal products contract development and manufacturing organization (CDMO) market are Thermo Fisher Scientific Inc., Merck KGaA, Resonac Corporation, Lonza Group AG, Catalent Inc., Charles River Laboratories International Inc., Recipharm AB, KBI Biopharma, Takara Bio Inc., Rentschler Biopharma SE, Ajinomoto Co. Inc., ElevateBio LLC, Fujifilm Diosynth Biotechnologies, Axplora Group GmbH, WuXi Advanced Therapies Inc., Celonic Group, Batavia Biosciences B.V., BioCentriq, Cytovance Biologics, Andelyn Biosciences, Genezen, AGC Biologics, ABL Manufacturing, Minaris Regenerative Medicine, Porton Advanced Solutions
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