RB fantasy football injury updates and reports for running backs in Week 6 (2025), as of October 8, including Omarion Hampton, Saquon Barkley, Chuba Hubbard, and Bucky Irving.
Below is our fantasy football injuries report for running backs in Week 6, as of October 8. The injury statuses for various NFL running backs are up in the air for Week 6, including Omarion Hampton, Saquon Barkley, Chuba Hubbard, Bucky Irving, and more.
As the fantasy football season gets underway, every decision, transaction, and lineup change matters. These are critical running back injuries to keep track of throughout the week. Being up-to-date on NFL injury news can give you an edge over your league mates in fantasy football.
To keep close tabs on all the news across the NFL, favorite or bookmark the fantasy football player news page, or download the free RotoBaller fantasy football mobile app with push notification alerts on all the latest news. Let’s look at the updates for some running backs and see whether they may play in Week 6.
Hampton (ankle) has been placed on injured reserve and will miss at least four weeks. The Chargers have been dealt some awful injury news lately, with Hampton sidelined and Najee Harris (Achilles) done for the year. Hassan Haskins and Kimani Vidal will split the bulk of the running back snaps going forward.
Barkley (knee) was listed as a limited participant in practice on Tuesday. The star running back is still trending toward playing on Thursday night, but managers should pay close attention to his status on the final injury report posted Wednesday afternoon.
Hubbard (calf) is day-to-day heading into Week 6, according to head coach Dave Canales. The Panthers’ primary running back missed last Sunday’s game, allowing Rico Dowdle to explode for over 200 yards. Even if Hubbard suits up this week, we’re likely looking at a split backfield in Carolina, given how well Dowdle played on Sunday.
Irving (foot, shoulder) is expected to miss at least one more week. While he’ll likely avoid being placed on injured reserve, he’ll have to be patient as he works his way back from injury. Rachaad White should handle at least one more game as the Bucs’ lead back.
Warren (knee) was seen practicing on Monday. While the Steelers don’t have to publish an injury report until Wednesday, it was promising to see Warren get back on the field, even in an unofficial capacity. He’s trending in the right direction for Week 6.
Giants head coach Brian Daboll is optimistic that Tracy (shoulder) will be able to play on Thursday night. He was estimated as a limited participant on Tuesday. It’s looking like Tracy will enter Week 6 listed as questionable. Even if he does play, he’s not a reliable fantasy starter now that Cam Skattebo has taken over the New York backfield.
Texans general manager Nick Caserio said that Mixon (foot) has made progress, but it remains unclear whether he’ll play in 2025. The team expects to have a better understanding of his season-long outlook over the next three to four weeks. In the meantime, Nick Chubb and Woody Marks will lead the Houston backfield.
Sanders (foot, ankle) sat out Sunday’s game against the Jets in Week 5. His status for Week 6 remains uncertain. Even if Sanders is active this week, he and Jaydon Blue would remain off the fantasy radar in their depth roles behind Javonte Williams.
Goodson (groin) did not play last Sunday against the Raiders. His status for Week 6 remains up in the air. If he can’t suit up, D.J. Giddens and Ameer Abdullah would occupy depth roles behind Jonathan Taylor.
Gibson (knee) tore his ACL during Sunday’s win over the Bills. His season is over. New England will search for a new No. 3 running back while Rhamondre Stevenson and TreVeyon Henderson continue to battle for the top spot on the depth chart.
The Bears have opened the 21-day practice window for Homer (calf). He remains on injured reserve but will be allowed to practice with the team for up to three weeks as they decide whether to activate him or shut him down. If activated, he’d primarily contribute on special teams.
Nwangwu (hamstring) will make the trip to London for Week 6 against the Broncos, according to Jets head coach Aaron Glenn. It’s too early to tell whether he’ll be active for the international contest. If he does play, he’d primarily contribute on special teams.
Here’s the full fantasy football injuries report, a quick hit list of all injured NFL players and their latest status. Be sure to also read the latest NFL injury news and updates for fantasy football.
