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What’s Behind the Strong Growth of the Addison’s Disease Market Size in the Last 5 Years?
The Addison’s disease market has seen robust growth in recent years, expanding from a size of $2.05 billion in 2024 to a projected value of $2.24 billion in 2025. This indicates a compound annual growth rate (CAGR) of 9.7%. This upward trend during the historical period has been driven by several factors including an increase in global occurrences of Addison’s disease, heightened awareness around adrenal insufficiency, a rise in health care spending, an increased frequency of autoimmune diseases, and a growing elderly population.
The market for Addison’s disease is forecasted to experience significant expansion in the forthcoming years. The market is estimated to amplify to $3.24 billion by 2029, with a compound annual growth rate (CAGR) of 9.6%. The upswing during the predicted period can be linked to the escalating demand for advanced treatment options, the increased emphasis on early detection, the growth in congenital adrenal hyperplasia cases, the development of telemedical services, and a heightened incidence of adrenal tuberculosis. Key trends for the forecasted period involve progress in laboratory testing procedures, improvements in hormone replacement therapies, technological advancements in imaging tools, the creation of extended-release injectable formulations, and the inclusion of artificial intelligence in diagnosis methodologies.
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What’s Driving the Upward Growth Trajectory of the Addison’s Disease Market?
The escalating rates of autoimmune diseases are anticipated to drive the growth of the market for Addison’s disease. Autoimmune diseases, which occur when the immune system mistakenly targets the individual’s own healthy tissues causing inflammation and damage, are becoming increasingly common. Factors including genetic predispositions, environmental elements such as pollutants and dietary shifts, and lifestyle changes like stress and decreased physical activity all factor into the escalated frequency of these diseases. As the occurrence of autoimmune diseases rises, the probability of them co-existing with Addison’s disease also increases, with many patients developing additional autoimmune disorders. For instance, data from Versorgungsatlas.de, a German organization, indicated that in 2022, out of 73,241,305 insured people, 6,304,340 were diagnosed with at least one autoimmune disease, signifying a raw prevalence rate of 8.61%, which is above previous evaluations ranging from 3% to 9%.
As such, the upswing in autoimmune diseases is influencing the growth of the Addison’s disease market.
Which Segments in the Addison’s Disease Industry Are Seeing the Fastest Growth?
The addison’s diseasemarket covered in this report is segmented –
1) By Type: Primary Adrenal Insufficiency; Secondary Adrenal Insufficiency; Tertiary Adrenal Insufficiency
2) By Drug Class: Oral Corticosteroid; Hydrocortisone; Fludrocortisone; Corticosteroid Injections
3) By Diagnosis: Laboratory Testing; Imaging Testing
4) By End-User: Hospitals And Clinics; Diagnostic Laboratories; Other End Users
Subsegments:
1) By Primary Adrenal Insufficiency: Autoimmune Addison’s Disease; Infectious Addison’s Disease; Other causes of primary adrenal insufficiency
2) By Secondary Adrenal Insufficiency: Pituitary gland dysfunction; Hypothalamic dysfunction
3) By Tertiary Adrenal Insufficiency: Hypothalamic or pituitary suppression due to long-term steroid use; Other causes of tertiary adrenal insufficiency
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How Will Shifting Market Trends Influence Addison’s Disease System Adoption?
Leading businesses in the Addison’s disease market are adopting innovative strategies such as regenerative therapies. The goal is to develop better treatment options, improve patient outcomes, and possibly reduce lifelong dependence on hormone replacement therapies by encouraging the body’s natural adrenal function. Regenerative therapies are medical procedures designed to replace or regenerate human cells, tissues, or organs, which can restore normal function and assist in healing during injury, disease, or degeneration. For example, Eton Pharmaceuticals, Inc., a US-based public pharmaceutical company specializing in developing and commercializing breakthrough treatments for rare diseases, declared in July 2024 that the FDA had accepted its New Drug Application (NDA) for ET-400, a unique formulation of oral hydrocortisone solution. Compared to other formulations requiring refrigeration, ET-400 is simpler to store and transport. The liquid form caters to the needs of young patients who may struggle with swallowing traditional tablets, allowing for accurate dosage.
Which Global Regions Are Powering Demand in the Addison’s Disease Market?
North America was the largest region in the addison’s disease market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the addison’s disease market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
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How Key Players Are Driving Growth in the Addison’s Disease Market?
Major companies operating in the addison’s disease market are Pfizer Inc., Roche Holding AG, Merck & Co. Inc., Bayer AG, Bristol-Myers Squibb Company, Novartis AG, Takeda Pharmaceutical Company Limited, GlaxoSmithKline plc, Amgen Inc., Teva Pharmaceutical Industries Ltd., Boehringer Ingelheim International GmbH, Sandoz, Ipsen S.A., Neurocrine Biosciences Inc., Recipharm AB, Accord Healthcare, Eton Pharmaceuticals, DuoCort Pharma, Diurnal Group plc, Roxane Laboratories Inc.
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